Yes diabetes makes you lose weight, with various things contributing to it. First the deficiency of insulin makes it difficult to store the needed nutrients like protein, carbohydrates and fats leading to increase in appetite, but loss of weight. In addition, fluid loss that occurs due to excess and frequent urination in an attempt to eliminate glucose results in dehydration, increased thirst and unintentional weight loss.

In addition, ketoacidosis resulting from high level of ketones in the body, with insufficient insulin to break them results in weight loss. In addition combination of fluid loss and high glucose levels could cause cachexia, extreme weight loss accompanied by fatigue, atrophied muscles, general bodily weakness and loss of appetite.

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